Hendricks et al. (2025) “Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice” Science Translational Medicine.
DOI: 10.1126/scitranslmed.adu2085
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about Hendricks et al. (2025) “Computationally designed mRNA-launched protein nanoparticle immunogens elicit protective antibody and T cell responses in mice” Science Translational Medicine.
Janjuha et al. (2025) “Spatial profiling of gene editing by in situ sequencing in mice and macaques” Nature Biomedical Engineering.
DOI: 10.1038/s41551-025-01512-7
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about Janjuha et al. (2025) “Spatial profiling of gene editing by in situ sequencing in mice and macaques” Nature Biomedical Engineering.
Limsalakpetch et al. (2025) “mRNA-LNP vaccine encoding the Plasmodium vivax circumsporozoite protein is highly immunogenic and confers protection in mice” Molecular Therapy Nucleic Acids.
DOI: 10.1016/j.omtn.2025.102645
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about Limsalakpetch et al. (2025) “mRNA-LNP vaccine encoding the Plasmodium vivax circumsporozoite protein is highly immunogenic and confers protection in mice” Molecular Therapy Nucleic Acids.
Limeres et al. (2025) “mRNA-LNP vaccines against hepatitis B virus induce protective immune responses in preventive and chronic mouse challenge models” Molecular Therapy.
DOI: 10.1016/j.ymthe.2025.06.027
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about Limeres et al. (2025) “mRNA-LNP vaccines against hepatitis B virus induce protective immune responses in preventive and chronic mouse challenge models” Molecular Therapy.
Shuvaev et al. (2025) “Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo” PNAS.
DOI: 10.1073/pnas.2409266122
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about Shuvaev et al. (2025) “Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo” PNAS.
Surisaeng et al. (2025) “BMP-2 mRNA-transfected BMSCs promote superior calvarial bone regeneration” Scientific Reports.
DOI: 10.1038/s41598-025-99979-6
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about Surisaeng et al. (2025) “BMP-2 mRNA-transfected BMSCs promote superior calvarial bone regeneration” Scientific Reports.
Acuitas Therapeutics named one of Canada’s Top Small & Medium Employers of 2025
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Acuitas Therapeutics named one of BC’s Top Employers of 2025
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Tremblay et al. (2025) “A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels” Nature Medicine.
DOI: 10.1038/s41591-025-03508-x
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about Tremblay et al. (2025) “A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels” Nature Medicine.
PUBLICATION ALERT: High-throughput quantification and characterization of dual payload mRNA/LNP cargo via deformulating size exclusion and ion pairing reversed phase assays
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Imiolek et al. (2025) “High-throughput quantification and characterization of dual payload mRNA/LNP cargo via deformulating size exclusion and ion pairing reversed phase assays” Analytical Chemistry.
DOI: 10.1021/acs.analchem.4c06296
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about Imiolek et al. (2025) “High-throughput quantification and characterization of dual payload mRNA/LNP cargo via deformulating size exclusion and ion pairing reversed phase assays” Analytical Chemistry.
PUBLICATION ALERT: Restoring hematopoietic stem and progenitor cell function in Fancc−/− mice by in situ delivery of RNA lipid nanoparticles
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