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Christopher Sweeney Named Executive Director, Intellectual Property

Read about Christopher Sweeney Named Executive Director, Intellectual Property

England et al. (2024) “Evaluation of mRNA-LNP and adjuvanted protein SARS-CoV-2 vaccines in a maternal antibody mouse model” NPJ Vaccines.

DOI: 10.1038/s41541-024-00901-4

Read about England et al. (2024) “Evaluation of mRNA-LNP and adjuvanted protein SARS-CoV-2 vaccines in a maternal antibody mouse model” NPJ Vaccines.

Smith et al. (2024) “Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice” Nature Communications.

DOI: 10.1038/s41467-024-49332-8

Read about Smith et al. (2024) “Transient growth factor expression via mRNA in lipid nanoparticles promotes hepatocyte cell therapy in mice” Nature Communications.

Parhiz et al. (2024) “Physiologically-based modeling of LNP-mediated delivery of mRNA in the vascular system” Molecular Therapy Nucleic Acids.

DOI: 10.1016/j.omtn.2024.102175

Read about Parhiz et al. (2024) “Physiologically-based modeling of LNP-mediated delivery of mRNA in the vascular system” Molecular Therapy Nucleic Acids.

Montoya et al. (2024) “mRNA-LNP vaccine-induced CD8+ T-cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies” Molecular Therapy.

DOI: 10.1016/j.ymthe.2024.04.019

Read about Montoya et al. (2024) “mRNA-LNP vaccine-induced CD8+ T-cells protect mice from lethal SARS-CoV-2 infection in the absence of specific antibodies” Molecular Therapy.

Furey et al. (2024) “Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus” Nature Communications.

DOI: 10.1038/s41467-024-48555-z

Read about Furey et al. (2024) “Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus” Nature Communications.

Wiehe et al. (2024) “Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction” Cell Host & Microbe.

DOI: 10.1016/j.chom.2024.04.006

Read about Wiehe et al. (2024) “Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction” Cell Host & Microbe.

Acuitas Poster Presentations at ASGCT Annual Meeting

Read about Acuitas Poster Presentations at ASGCT Annual Meeting

Nong et al. (2024) “Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke” Molecular Therapy.

DOI: 10.1016/j.ymthe.2024.03.004

Read about Nong et al. (2024) “Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke” Molecular Therapy.

Acuitas Therapeutics Named One of Canada’s Top Small & Medium Employers of 2024

Read about Acuitas Therapeutics Named One of Canada’s Top Small & Medium Employers of 2024

Tafech et al. (2024) “Exploring mechanisms of lipid nanoparticle-mucus interactions in healthy and cystic fibrosis conditions” Advanced Healthcare Materials.

DOI: 10.1002/adhm.202304525

Read about Tafech et al. (2024) “Exploring mechanisms of lipid nanoparticle-mucus interactions in healthy and cystic fibrosis conditions” Advanced Healthcare Materials.

Tilsed et al. (2024) “IL7 increases targeted lipid nanoparticle–mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation” PNAS.

DOI: 10.1073/pnas.2319856121

Read about Tilsed et al. (2024) “IL7 increases targeted lipid nanoparticle–mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation” PNAS.